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Immobilization of Protein Molecules by Size‐Selected Metal Clusters on Surfaces
Author(s) -
Leung C.,
Xirouchaki C.,
Berovic N.,
Palmer R. E.
Publication year - 2004
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200305756
Subject(s) - monolayer , materials science , atomic force microscopy , molecule , nanotechnology , metal , chemical physics , phase (matter) , crystallography , organic chemistry , chemistry , metallurgy
Protein immobilization by nanocluster films is a new route to stabilize individual protein molecules and complexes for single‐molecule measurements such as liquid‐phase atomic force microscopy (AFM) imaging (see Figure). The sub‐monolayer films of size‐selected Au clusters present protein binding sites of arbitrary density.