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Hydrogel Formation via Cell Crosslinking
Author(s) -
Lee K.Y.,
Kong H.J.,
Larson R.G.,
Mooney D.J.
Publication year - 2003
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200305406
Subject(s) - materials science , ligand (biochemistry) , polymer , nanotechnology , biophysics , polymer science , receptor , composite material , biochemistry , chemistry , biology
It is demonstrated that cells can be utilized as a crosslinker to form network structures from polymers. The properties of these systems can be interpreted with classical network theory. This approach can be useful to determine various parameters related to cell receptor–ligand binding (see Figure), such as the number of bonds, as well as to suggest a unique means to the delivery of cells for therapeutic purposes.