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Entrapment of biocatalysts in hydrophobic sol‐gel materials for use in organic chemistry
Author(s) -
Reetz Manfred T.
Publication year - 1997
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.19970091203
Subject(s) - catalysis , entrapment , lipase , materials science , organic chemistry , chemical engineering , immobilized enzyme , polymer , chemistry , nanotechnology , enzyme , medicine , surgery , engineering
Lipases trapped in hydrophobic organic/inorganic materials result in chemically and thermally stable heterogeneous catalysts that display unusually high catalytic activities. The entrapment of lipases and other biocatalysts by sol‐gel encapsulation is an interesting approach to enzyme immobilization, which has the aim of increasing enzyme activity in organic solvents. Investigations that have been carried out to optimize encapsulation and to characterize the lipase‐containing gels are reviewed. Possible applications in organic synthesis are indicated.