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The effects of DC electric currents on the in‐vitro calcification of bioactive silicon wafers
Author(s) -
Canham Leigh T.,
Newey Jon P.,
Reeves Chris L.,
Houlton Mike R.,
Loni Armando,
Simons Andrew J.,
Cox Timothy I.
Publication year - 1996
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.19960081019
Subject(s) - materials science , silicon , wafer , porous silicon , calcium , deposition (geology) , biomaterial , cathodic protection , phosphate , calcification , layer (electronics) , nanotechnology , chemical engineering , optoelectronics , electrode , metallurgy , electrochemistry , chemistry , biochemistry , medicine , paleontology , pathology , sediment , biology , engineering
That silicon could become an important tissue‐compatible biomaterial is suggested by recent results. First observations are reported here of the significant effects that electrical bias has on the calcification process under simulated a cellular physiological conditions. Cathodic current flow through porous silicon is shown to accelerate the kinetics of calcium phosphate deposition. Reasons why formation is restricted to the cathodically biased region and why calcium phosphate is not formed within the silicon layer are discussed.

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