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Microfluidic Tandem Mechanical Sorting System for Enhanced Cancer Stem Cell Isolation and Ingredient Screening (Adv. Healthcare Mater. 20/2021)
Author(s) -
Jia Yuanyuan,
Shen Peiliang,
Yan Tao,
Zhou Weijia,
Sun Jia,
Han Xin
Publication year - 2021
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202170099
Subject(s) - cancer stem cell , stem cell , cell sorting , microfluidics , isolation (microbiology) , drug delivery , sorting , nanotechnology , tandem , flexibility (engineering) , cancer cell , cancer research , cancer , materials science , medicine , microbiology and biotechnology , flow cytometry , biology , immunology , bioinformatics , computer science , statistics , mathematics , composite material , programming language
Cancer Stem Cells In article number 2100985 by Jia Sun, Xin Han, and co‐workers, a microfluidic tandem mechanical sorting strategy is reported to enrich cancer stem cells (CSCs) with high flexibility and low adhesive capacity. The method achieves robust isolation of CSCs in a high‐throughput, label‐free manner, which has promising potential for facilitating drug screening targeting CSCs and developing novel therapeutic strategies overcoming drug resistance.