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Mechanical Properties of Bioengineered Corneal Stroma (Adv. Healthcare Mater. 20/2021)
Author(s) -
Formisano Nello,
Putten Cas,
Grant Rhian,
Sahin Gozde,
Truckenmüller Roman K.,
Bouten Carlijn V. C.,
Kurniawan Nicholas A.,
Giselbrecht Stefan
Publication year - 2021
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202170094
Subject(s) - economic shortage , stromal cell , stroma , cornea , nanotechnology , medicine , biomedical engineering , materials science , pathology , ophthalmology , philosophy , linguistics , immunohistochemistry , government (linguistics)
Corneas In article number 2100972, Stefan Giselbrecht and colleagues review existing approaches for bioengineering corneal stromal constructs. There is a high demand for bioengineered corneal constructs to overcome a global donor shortage, but unfortunately many of these bioengineered constructs fail clinical trials due to poor biomechanical performance. This review emphasizes the need to more critically design and analyze these properties in future stromal constructs.