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Corneal Microneedles: Single Administration of a Biodegradable, Separable Microneedle Can Substitute for Repeated Application of Eyedrops in the Treatment of Infectious Keratitis (Adv. Healthcare Mater. 11/2021)
Author(s) -
Park SeungHyun,
Lee KangJu,
Kang Heekyoung,
Lee YeJin,
Lee JiYong,
Kim Jeong Hun,
Song Hyun Beom,
Ryu WonHyoung
Publication year - 2021
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202170054
Subject(s) - keratitis , cornea , medicine , in vivo , biomedical engineering , materials science , dermatology , ophthalmology , biology , microbiology and biotechnology
In article number 2002287 by WonHyoung Ryu, Hyun Beom Song, and co‐workers, a biodegradable and separable microneedle into the cornea is studied as a substitute for multiple eyedrops in the treatment of infectious keratitis. This study showcases the mechanical integrity and release optimization with three different formulations of drug‐tip and demonstrates that a single microneedle injection can be used instead of an initial three days of multiple eyedrops in vivo.