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Nanoparticle Association: In Vivo Quantification of Nanoparticle Association with Immune Cell Subsets in Blood (Adv. Healthcare Mater. 9/2021)
Author(s) -
Ong Yih Rue,
De Rose Robert,
Johnston Angus P. R.
Publication year - 2021
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202170043
Subject(s) - in vivo , ex vivo , white blood cell , nanoparticle , immune system , medicine , immunology , materials science , biology , nanotechnology , microbiology and biotechnology
The clearance of nanoparticles in vivo is mediated by circulating white blood cells. In article number 2002160, Angus P. R. Johnston and co‐workers develop an assay that quantifies the in vivo interactions of nanoparticles with different subsets of circulating white blood cells, which shows significant differences to the association observed between nanoparticles and white blood cells ex vivo. The cover image shows an artistic representation of blue nanoparticles binding to white blood cells in a capillary.