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Biomimetic Peptides: An Engineered Biomimetic Peptide Regulates Cell Behavior by Synergistic Integrin and Growth Factor Signaling (Adv. Healthcare Mater. 7/2021)
Author(s) -
OliverCervelló Lluís,
MartinGómez Helena,
Reyes Leslie,
Noureddine Fatima,
Ada CavalcantiAdam Elisabetta,
Ginebra MariaPau,
MasMoruno Carlos
Publication year - 2021
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202170032
Subject(s) - peptide , integrin , c2c12 , growth factor , microbiology and biotechnology , cell growth , rgd motif , cell , materials science , 3t3 cells , cell culture , chemistry , receptor , biochemistry , biology , transfection , myogenesis , myocyte , genetics
Stimulating integrin and growth factor signaling is a major goal to regulate cell‐material interactions. This cover shows a biomimetic peptide containing the RGD cell adhesive motif and the osteogenic DWIVA sequence anchored to a glass model substrate. This work can be found in article number 2001757 by Carlos Mas‐Moruno and co‐workers. Such functionalized surface fine‐tuned the behavior of C2C12 cells in a synergistic manner.