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Neoantigen Harvesting: Self‐Adjuvanted Molecular Activator (SeaMac) Nanovaccines Promote Cancer Immunotherapy (Adv. Healthcare Mater. 7/2021)
Author(s) -
Luo Zichao,
He Tao,
Liu Peng,
Yi Zhigao,
Zhu Shunyao,
Liang Xiuqi,
Kang Entang,
Gong Changyang,
Liu Xiaogang
Publication year - 2021
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202170025
Subject(s) - cancer immunotherapy , immunotherapy , cancer research , cancer therapy , abscopal effect , immune system , activator (genetics) , medicine , cancer , immunology , receptor
In article number 2002080, Xiaogang Liu, Changyang Gong, and co‐workers, design functional bio‐nanoprobes with STING‐activating and neoantigen‐capturing abilities for personalized tumor immunotherapy. After photodynamic therapy, the bio‐nanoprobes can harvest neoantigens to form SeaMac nanovaccines. The nanovaccines subsequently promote abscopal effects without immune checkpoint inhibitors.