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Photodynamic Therapy: Radioiodinated Persistent Luminescence Nanoplatform for Radiation‐Induced Photodynamic Therapy and Radiotherapy (Adv. Healthcare Mater. 5/2021)
Author(s) -
Wang Qiang,
Liu Nian,
Hou Zhenyu,
Shi Junpeng,
Su Xinhui,
Sun Xiaolian
Publication year - 2021
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202170017
Subject(s) - photodynamic therapy , radiation therapy , photosensitizer , cancer research , in vivo , medicine , luminescence , materials science , chemistry , photochemistry , optoelectronics , biology , organic chemistry , microbiology and biotechnology
In article number 2000802 by Xinhui Su, Xiaolian Sun, and co‐workers, a 131 I labeled ZnPc(COOH) 4 conjugated ZnGa2O 4 :Cr 3+ nanoplatform ( 131 I‐ZGCs‐ZnPcC4) is developed for in vivo radiotherapy (RT) and radiation‐induced photodynamic therapy (PDT). 131 I can not only activate ZGCs for long‐lasting luminescence which further continuously activates the photosensitizer for PDT, but also can directly kill cancerous cells. Combining self‐activated PDT and RT, it is believed that the 131 IZGCs‐ ZnPcC 4 can greatly benefit deep tumor therapy.