Premium
Cell Encapsulation: Enhanced In Vivo Vascularization of 3D‐Printed Cell Encapsulation Device Using Platelet‐Rich Plasma and Mesenchymal Stem Cells (Adv. Healthcare Mater. 19/2020)
Author(s) -
PaezMayorga Jesus,
Capuani Simone,
Farina Marco,
Lotito Maria Luisa,
Niles Jean A.,
Salazar Hector F.,
Rhudy Jessica,
Esnaola Lucas,
Chua Corrine Ying Xuan,
Taraballi Francesca,
Corradetti Bruna,
Shelton Kathryn A.,
Nehete Pramod N.,
Nichols Joan E.,
Grattoni Alessandro
Publication year - 2020
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202070071
Subject(s) - mesenchymal stem cell , cell encapsulation , vascularity , encapsulation (networking) , in vivo , biomedical engineering , platelet rich plasma , stem cell , transplantation , materials science , cell , tissue engineering , microbiology and biotechnology , medicine , platelet , chemistry , pathology , immunology , biology , surgery , computer network , biochemistry , computer science
In article number 2000670 by Alessandro Grattoni and co‐workers, vascularization of a subcutaneously implantable cell encapsulation platform is enhanced via enrichment with plateletrich plasma (PRP) and mesenchymal stem cells (MSCs) in rats and non‐human primates. Timepoint vascularity assessment demonstrates enrichment with PRP and MSCs increases blood vessel density and maturity inside the encapsulation devices, unveiling an optimal window for cell transplantation. Interspecies reproducibility points toward translatability of the technology.