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Bone Regeneration: A Multi‐Functional Implant Induces Bone Formation in a Diabetic Model (Adv. Healthcare Mater. 18/2020)
Author(s) -
Khorsand Behnoush,
Acri Timothy M.,
Do AnhVu,
Femino John E.,
Petersen Emily,
Fredericks Douglas C.,
Salem Aliasger K.
Publication year - 2020
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202070063
Subject(s) - regeneration (biology) , bone formation , medicine , scaffold , bone healing , microbiology and biotechnology , endocrinology , biomedical engineering , anatomy , biology
In article number 2000770 by Aliasger K. Salem and co‐workers, the local delivery of insulin, Vitamin D3 metabolites, and BMP‐2 and FGF‐2 genes from a collagen scaffold is investigated to promote bone formation in Type‐2 diabetic rats. The ectopic formation of bone in diabetic rats suggests this approach has strong potential for bone regeneration in diabetic patients.