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Computer‐aided Drug Design: Additive Manufacturing of a Point‐of‐Care “Polypill:” Fabrication of Concept Capsules of Complex Geometry with Bespoke Release against Cardiovascular Disease (Adv. Healthcare Mater. 13/2020)
Author(s) -
Pereira Beatriz C.,
Isreb Abdullah,
Isreb Mohammad,
Forbes Robert T.,
Oga Enoche F.,
Alhnan Mohamed A.
Publication year - 2020
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202070042
Subject(s) - bespoke , polypill , modular design , drug , health care , fabrication , computer science , medicine , nanotechnology , biomedical engineering , materials science , engineering drawing , manufacturing engineering , pharmacology , disease , engineering , business , pathology , alternative medicine , advertising , economics , economic growth , operating system
In article number 2000236 by Enoche F. Oga, Mohamed A. Alhnan, and co‐workers a novel design approach is employed to fabricate highly modular 3D printed “polypill” capsules with bespoke release patterns for multiple drugs. Complex structures are devised to achieve dose individualization. In silico pharmacokinetic projections of the developed capsules highlight how healthcare staff can adapt complex therapeutic regimens to each patient.