Premium
Therapeutic Resevoirs: Implantable Therapeutic Reservoir Systems for Diverse Clinical Applications in Large Animal Models (Adv. Healthcare Mater. 11/2020)
Author(s) -
Duffy Garry P.,
Robinson Scott T.,
O'Connor Raymond,
Wylie Robert,
Mauerhofer Ciaran,
Bellavia Gabriella,
Straino Stefania,
Cianfarani Francesca,
Mendez Keegan,
Beatty Rachel,
Levey Ruth,
O'Sullivan Janice,
McDonough Liam,
Kelly Helena,
Roche Ellen T.,
Dolan Eimear B.
Publication year - 2020
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202070035
Subject(s) - scalability , medicine , computer science , intensive care medicine , biomedical engineering , neuroscience , biology , database
In article number 2000305 by Ellen T. Roche, Eimear B. Dolan, and co‐workers, a new regenerative reservoir platform (Regenervoir) is described for use in large animal models that are easily translated to human studies, with relevance to cardiac, abdominal, and soft tissue pathologies. Regenervoir incorporates multiple novel design features essential for clinical translation, with a focus on scalability, mechanism of delivery, fixation, and filling/refilling with a therapeutic cargo.