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Cardiac Microtissues: Maladaptive Contractility of 3D Human Cardiac Microtissues to Mechanical Nonuniformity (Adv. Healthcare Mater. 8/2020)
Author(s) -
Wang Chenyan,
Koo Sangmo,
Park Minok,
Vangelatos Zacharias,
Hoang Plansky,
Conklin Bruce R.,
Grigoropoulos Costas P.,
Healy Kevin E.,
Ma Zhen
Publication year - 2020
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202070024
Subject(s) - contractility , induced pluripotent stem cell , human induced pluripotent stem cells , biomedical engineering , tissue engineering , human heart , microbiology and biotechnology , medicine , anatomy , materials science , cardiology , chemistry , biology , embryonic stem cell , biochemistry , gene
In article number 1901373 by Kevin E. Healy, Zhen Ma, and co‐workers, a “pathologically‐inspired” 3D cardiac microtissue model is established based on human induced pluripotent stem cells and laser‐based 3D printing technology. This engineered in vitro model system can facilitate better understanding of the correlation between cardiac contractile dysfunctions and nonuniform tissue mechanical environments.