Bone Replacement: The Secretome of Hypoxia Conditioned hMSC Loaded in a Central Depot Induces Chemotaxis and Angiogenesis in a Biomimetic Mineralized Collagen Bone Replacement Material (Adv. Healthcare Mater. 2/2020) | Zendy

Quade Mandy | Zendy; Münch Pina | Zendy; Lode Anja | Zendy; Duin Sarah | Zendy; Vater Corina | Zendy; Gabrielyan Anastasia | Zendy; RösenWolff Angela | Zendy; Gelinsky Michael | Zendy

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Bone Replacement: The Secretome of Hypoxia Conditioned hMSC Loaded in a Central Depot Induces Chemotaxis and Angiogenesis in a Biomimetic Mineralized Collagen Bone Replacement Material (Adv. Healthcare Mater. 2/2020)

Author(s) -

Quade Mandy,

Münch Pina,

Lode Anja,

Duin Sarah,

Vater Corina,

Gabrielyan Anastasia,

RösenWolff Angela,

Gelinsky Michael

Publication year - 2020

Publication title -

advanced healthcare materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.288

H-Index - 90

eISSN - 2192-2659

pISSN - 2192-2640

DOI - 10.1002/adhm.202070005

Subject(s) - angiogenesis , chemotaxis , bone healing , biomedical engineering , hypoxia (environmental) , microbiology and biotechnology , materials science , chemistry , medicine , cancer research , biology , anatomy , biochemistry , receptor , organic chemistry , oxygen

In article number 1901426 by Anja Lode and co‐workers, sustained release of hypoxia‐conditioned MSC secretome from a central depot induces directed hBMSC migration and angiogenesis in biomimetic mineralized collagen scaffolds. This in situ tissue engineering concept is suggested to be a cell‐free and ready‐to‐use therapeutic solution for accelerated bone defect healing.

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