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Silk‐Based Biomaterials for Cardiac Tissue Engineering
Author(s) -
Song Yu,
Wang Huifang,
Yue Feifei,
Lv Qiying,
Cai Bo,
Dong Nianguo,
Wang Zheng,
Wang Lin
Publication year - 2020
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.202000735
Subject(s) - tissue engineering , biocompatibility , self healing hydrogels , silk , biomedical engineering , biocompatible material , biomaterial , nanotechnology , materials science , medicine , polymer chemistry , metallurgy , composite material
Cardiovascular diseases are one of the leading causes of death globally. Among various cardiovascular diseases, myocardial infarction is an important one. Compared with conventional treatments, cardiac tissue engineering provides an alternative to repair and regenerate the injured tissue. Among various types of materials used for tissue engineering applications, silk biomaterials have been increasingly utilized due to their biocompatibility, biological functions, and many favorable physical/chemical properties. Silk biomaterials are often used alone or in combination with other materials in the forms of patches or hydrogels, and serve as promising delivery systems for bioactive compounds in tissue engineering repair scenarios. This review focuses primarily on the promising characteristics of silk biomaterials and their recent advances in cardiac tissue engineering.