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Nerve Regeneration: Repairing Transected Peripheral Nerve Using a Biomimetic Nerve Guidance Conduit Containing Intraluminal Sponge Fillers (Adv. Healthcare Mater. 21/2019)
Author(s) -
Hou Yuanjing,
Wang Xinyu,
Zhang Zongrui,
Luo Jing,
Cai Zhengwei,
Wang Yiyu,
Li Yi
Publication year - 2019
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201970082
Subject(s) - regeneration (biology) , nerve guidance conduit , electrical conduit , peripheral nerve , extracellular matrix , sponge , materials science , biomedical engineering , anatomy , medicine , biology , microbiology and biotechnology , computer science , telecommunications , botany
Repair of segmental nerve defects remains a troublesome issue in the clinic. In article number 1900913 by Xinyu Wang and co‐workers, an innovative nerve guide conduit (ISF‐NGC) is constructed by combining a nanofibrous external conduit and intraluminal sponge fillers. The ISF‐NGC provides extracellular matrix (ECM)‐like architecture for axonal regrowth and effectively facilitates nerve regeneration.