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Interfaces: Cellular and Chemical Gradients to Engineer the Meniscus‐to‐Bone Insertion (Adv. Healthcare Mater. 7/2019)
Author(s) -
Iannucci Leanne E.,
Boys Alexander J.,
McCorry Mary Clare,
Estroff Lara A.,
Bonassar Lawrence J.
Publication year - 2019
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201970027
Subject(s) - meniscus , materials science , structuring , biomedical engineering , bioreactor , nanotechnology , composite material , chemistry , engineering , optics , physics , incidence (geometry) , finance , economics , organic chemistry
In article number 1800806 by Lawrence J. Bonassar and co‐workers, a tissue engineered meniscal insertion is generated using compositional, cellular, and chemical gradients. Constructs are subjected to chemical and mechanical conditioning through a custom bioreactor. Utilization of cellular and chemical gradients results in constructs with localized interfacial structuring, collagen fiber development, and improved mechanical performance with respect to controls.