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Macroporous Scaffolds: A 3D Macroporous Alginate Graphene Scaffold with an Extremely Slow Release of a Loaded Cargo for In Situ Long‐Term Activation of Dendritic Cells (Adv. Healthcare Mater. 5/2019)
Author(s) -
Sinha Arjyabaran,
Choi Youngjin,
Nguyen Minh Hoang,
Nguyen Thanh Loc,
Choi Seung Woo,
Kim Jaeyun
Publication year - 2019
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201970016
Subject(s) - scaffold , materials science , in situ , graphene , nanotechnology , dendritic cell , biophysics , chemistry , biomedical engineering , immune system , immunology , medicine , biology , organic chemistry
In article number 1800571 by Jaeyun Kim and co‐workers, a three‐dimensional alginate scaffold embedded with reduced graphene oxide, characterized with high loading and slow release properties, is synthesized for long‐term in situ modulation of dendritic cells to enhance vaccine efficacy. After mice are vaccinated with the scaffold loaded with immuno‐active molecules, this scaffold suppresses tumor growth by significant activation of dendritic cells and cytotoxic T cells for a long time.