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Organ‐on‐a‐Chip: Organ‐on‐a‐Chip for Cancer and Immune Organs Modeling (Adv. Healthcare Mater. 4/2019)
Author(s) -
Sun Wujin,
Luo Zhimin,
Lee Junmin,
Kim HanJun,
Lee KangJu,
Tebon Peyton,
Feng Yudi,
Dokmeci Mehmet R.,
Sengupta Shiladitya,
Khademhosseini Ali
Publication year - 2019
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201970014
Subject(s) - organ on a chip , immune system , chip , cancer , materials science , healthcare system , nanotechnology , medicine , cancer research , biomedical engineering , health care , computer science , immunology , political science , telecommunications , microfluidics , law
In article number 1801363 Shiladitya Sengupta, Ali Khademhosseini and co‐workers show organ‐on‐a‐chip systems can provide high‐throughput platforms for drug development, which could potentially bridge the gap between 2D cell culture and animal models. With recent breakthroughs in anticancer immunotherapies, there is an increasing interest in organotypic models for anti‐cancer immunotherapy development. This study reviews current progress in cancer‐on‐a‐chip and immune organ‐on‐a‐chip systems with an emphasis on their potential for drug development.