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Bone Regeneration: Embryonic‐Like Mineralized Extracellular Matrix/Stem Cell Microspheroids as a Bone Graft Substitute (Adv. Healthcare Mater. 19/2018)
Author(s) -
Fu Cuicui,
Luo Dan,
Yu Min,
Jiang Nan,
Liu Dawei,
He Danqing,
Fu Yu,
Zhang Ting,
Qiao Yiqiang,
Zhou Yanheng,
Liu Yan
Publication year - 2018
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201870076
Subject(s) - extracellular matrix , embryonic stem cell , regeneration (biology) , microbiology and biotechnology , stem cell , scaffold , materials science , bone healing , transplantation , regenerative medicine , biomedical engineering , tissue engineering , matrix (chemical analysis) , chemistry , anatomy , medicine , biology , surgery , biochemistry , composite material , gene
In article 1800705 , Yanheng Zhou, Yan Liu, and co‐workers, fabricate embryonic‐like mineralized extracellular matrix/stem cell microspheroids (MECS), which provide a physiological microenvironment conducive to intracellular communication and osteogenesis, leading to excellent bone regeneration outcomes. This study demonstrates the feasibility of MECS transplantation as a promising scaffold‐free strategy for cell‐based bone regenerative therapy in tissue engineering.