Premium
Antibody‐Based Therapeutics: Ultrasensitive NIR‐SERRS Probes with Multiplexed Ratiometric Quantification for In Vivo Antibody Leads Validation (Adv. Healthcare Mater. 4/2018)
Author(s) -
Kang Homan,
Jeong Sinyoung,
Jo Ahla,
Chang Hyejin,
Yang JinKyoung,
Jeong Cheolhwan,
Kyeong San,
Lee Youn Woo,
Samanta Animesh,
Maiti Kaustabh Kumar,
Cha Myeong Geun,
Kim TaekKeun,
Lee Sukmook,
Jun BongHyun,
Chang YoungTae,
Chung Junho,
Lee HoYoung,
Jeong Dae Hong,
Lee YoonSik
Publication year - 2018
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201870019
Subject(s) - in vivo , raman scattering , materials science , raman spectroscopy , nanotechnology , chemistry , optics , biology , physics , microbiology and biotechnology
In article number 1700870 , Yoon‐Sik Lee and co‐workers demonstrate in vivo validation process of candidate antibodies against human colon cancer, using a ratiometric quantification method. The validation is performed on a single mouse and analyzed by multiplexed surface‐enhanced resonance Raman scattering (SERRS) with ultrasensitive and near‐infrared (NIR)‐active SERRS nanoprobes (NIR‐SERRS dots).