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Nitric Oxide Therapy for Diabetic Wound Healing
Author(s) -
MalonePovolny Maggie J.,
Maloney Sara E.,
Schoenfisch Mark H.
Publication year - 2019
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201801210
Subject(s) - wound healing , nitric oxide , medicine , inflammation , diabetes mellitus , intensive care medicine , endogeny , pharmacology , surgery , immunology , endocrinology
Nitric oxide (NO) represents a potential wound therapeutic agent due to its ability to regulate inflammation and eradicate bacterial infections. Two broad strategies exist to utilize NO for wound healing; liberating NO from endogenous reservoirs, and supplementing NO from exogenous sources. This progress report examines the efficacy of a variety of NO‐based methods to improve wound outcomes, with particular attention given to diabetes‐associated chronic wounds.