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Nerve Regeneration: Human Periodontal Ligament‐ and Gingiva‐derived Mesenchymal Stem Cells Promote Nerve Regeneration When Encapsulated in Alginate/Hyaluronic Acid 3D Scaffold (Adv. Healthcare Mater. 24/2017)
Author(s) -
Ansari Sahar,
Diniz Ivana M.,
Chen Chider,
Sarrion Patricia,
Tamayol Ali,
Wu Benjamin M.,
Moshaverinia Alireza
Publication year - 2017
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201770121
Subject(s) - regeneration (biology) , mesenchymal stem cell , periodontal fiber , hyaluronic acid , stem cell , periodontal ligament stem cells , scaffold , tissue engineering , nerve growth factor , nerve guidance conduit , microbiology and biotechnology , regenerative medicine , anatomy , biomedical engineering , dentistry , chemistry , pathology , medicine , biology , biochemistry , alkaline phosphatase , receptor , enzyme
Sahar Ansari and co‐workers fabricate a 3D delivery system based on alginate/hyaluronic hydrogel in article number 1700670 . The Encapsulated Periodontal Ligament Stem Cells and Gingival Mesenchymal Stem Cells demonstrate positive β ‐tubulin III staining after four weeks of in vitro differentiation in the presence of recombinant human nerve growth factor ( β ‐NGF) and high levels of gene expression related to neurogenic differentiation. This system has the potential to be used for cell therapy in the repair or regeneration of damaged nerves.