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Antibacterial Activity of Silver Nanoparticles: Structural Effects
Author(s) -
Tang Shaoheng,
Zheng Jie
Publication year - 2018
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201701503
Subject(s) - silver nanoparticle , nanotechnology , antimicrobial , antibacterial activity , nanoparticle , broad spectrum , antibiotic resistance , antibiotics , multiple drug resistance , bacteria , materials science , chemistry , microbiology and biotechnology , combinatorial chemistry , biology , genetics
The increase of antibiotic resistance in bacteria has become a major concern for successful diagnosis and treatment of infectious diseases. Over the past few decades, significant progress has been achieved on the development of nanotechnology‐based medicines for combating multidrug resistance in microorganisms. Among this, silver nanoparticles (AgNPs) hold great promise in addressing this challenge due to their broad‐spectrum and robust antimicrobial properties. This review illustrates the antibacterial mechanisms of silver nanoparticles and further elucidates how different structural factors including surface chemistry, size, and shape, impact their antibacterial activities, which are expected to promote the future development of more potent silver nanoparticle‐based antibacterial agents.