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Fast Setting Silk Fibroin Bioink for Bioprinting of Patient‐Specific Memory‐Shape Implants
Author(s) -
Costa João B.,
SilvaCorreia Joana,
Oliveira Joaquim M.,
Reis Rui L.
Publication year - 2017
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201701021
Subject(s) - fibroin , 3d bioprinting , materials science , biomedical engineering , nanotechnology , silk , computer science , tissue engineering , composite material , engineering
The pursuit for the “perfect” biomimetic and personalized implant for musculoskeletal tissue regeneration remains a big challenge. 3D printing technology that makes use of a novel and promising biomaterials can be part of the solution. In this study, a fast setting enzymatic‐crosslinked silk fibroin (SF) bioink for 3D bioprinting is developed. Their properties are fine‐tuned and different structures with good resolution, reproducibility, and reliability can be fabricated. Many potential applications exist for the SF bioinks including 3D bioprinted scaffolds and patient‐specific implants exhibiting unique characteristics such as good mechanical properties, memory‐shape feature, suitable degradation, and tunable pore architecture and morphology.