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Egg Albumen as a Fast and Strong Medical Adhesive Glue
Author(s) -
Xu Kaige,
Liu Yuqing,
Bu Shousan,
Wu Tianyi,
Chang Qiang,
Singh Gurankit,
Cao Xiaojian,
Deng Chuang,
Li Bingyun,
Luo Gaoxing,
Xing Malcolm
Publication year - 2017
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201700132
Subject(s) - adhesive , materials science , glue , polydimethylsiloxane , composite material , fabrication , wound closure , covalent bond , nanotechnology , wound healing , layer (electronics) , surgery , chemistry , pathology , medicine , alternative medicine , organic chemistry
Abstract Sutures penetrate tissues to close wounds. This process leads to inflammatory responses, prolongs healing time, and increases operation complexity. It becomes even worse when sutures are applied to stress‐sensitive and fragile tissues. By bonding tissues via forming covalent bonds, some medical adhesives are not convenient to be used by surgeons and have side effects to the tissues. Here egg albumen adhesive (EAA) is reported with ultrahigh adhesive strength to bond various types of materials and can be easily used without any chemical and physical modifications. Compared with several commercial medical glues, EAA exhibits stronger adhesive property on porcine skin, glass, polydimethylsiloxane. The EAA also shows exceptional underwater adhesive strength. Finally, wound closure using EAA on poly(caprolactone) nanofibrous sheet and general sutures is investigated and compared in a rat wound model. EAA also does not show strong long‐term inflammatory response, suggesting that EAA has potential as a medical glue, considering its abundant source, simple fabrication process, inherent nontoxicity, and low cost.