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Electrospinning: A Bioinspired Ultraporous Nanofiber‐Hydrogel Mimic of the Cartilage Extracellular Matrix (Adv. Healthcare Mater. 24/2016)
Author(s) -
Formica Florian A.,
Öztürk Ece,
Hess Samuel C.,
Stark Wendelin J.,
ManiuraWeber Katharina,
Rottmar Markus,
ZenobiWong Marcy
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201670131
Subject(s) - materials science , electrospinning , nanofiber , chondrogenesis , sublimation (psychology) , composite number , cartilage , biofabrication , extracellular matrix , polymer , nanotechnology , biomedical engineering , tissue engineering , composite material , chemistry , anatomy , medicine , biochemistry , psychology , psychotherapist
M. Zenobi‐Wong and co‐workers develop cell‐seeded, ultraporous composite scaffolds for cartilage regeneration on page 3129. By means of cryoelectrospinning, ice crystals are co‐deposited with the polymer. After sublimation, macropores are created which subsequently allow the infiltration of the electrospun membrane with a cell/hydrogel suspension. This procedure provides mechanical stability to the weak but chondrogenic alginate sulfate hydrogel.