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3D Bioprinting: 3D Bioprinting of Developmentally Inspired Templates for Whole Bone Organ Engineering (Adv. Healthcare Mater. 18/2016)
Author(s) -
Daly Andrew C.,
Cunniffe Gráinne M.,
Sathy Binulal N.,
Jeon Oju,
Alsberg Eben,
Kelly Daniel J.
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201670100
Subject(s) - biofabrication , 3d bioprinting , cartilage , biomedical engineering , template , tissue engineering , in vivo , materials science , nanotechnology , anatomy , medicine , biology , microbiology and biotechnology
A novel biofabrication strategy is described by Daniel R. Kelly and co‐workers. On page 2353, 3D bioprinting is used to engineer the developmental precursor to an adult organ. These bioprinted cartilage templates have the capacity to mature into vascularized bone organs in vivo. It is possible to reinforce these immature cartilage precursors with poly‐caprolactone microfibres, providing a level of mechanical functionality compatible with implanting such immature organ rudiments into load bearing locations in vivo.