Alzheimer Therapy: Photoactive g‐C 3 N 4  Nanosheets for Light‐Induced Suppression of Alzheimer's β‐Amyloid Aggregation and Toxicity (Adv. Healthcare Mater. 13/2016) | Zendy

Chung You Jung | Zendy; Lee Byung Il | Zendy; Ko Jong Wan | Zendy; Park Chan Beum | Zendy

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Alzheimer Therapy: Photoactive g‐C 3 N 4 Nanosheets for Light‐Induced Suppression of Alzheimer's β‐Amyloid Aggregation and Toxicity (Adv. Healthcare Mater. 13/2016)

Author(s) -

Chung You Jung,

Lee Byung Il,

Ko Jong Wan,

Park Chan Beum

Publication year - 2016

Publication title -

advanced healthcare materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.288

H-Index - 90

eISSN - 2192-2659

pISSN - 2192-2640

DOI - 10.1002/adhm.201670064

Subject(s) - amyloid (mycology) , amyloid β , biophysics , alzheimer's disease , graphitic carbon nitride , chemistry , materials science , neuroscience , medicine , disease , biochemistry , psychology , biology , pathology , photocatalysis , catalysis

The accumulation of β‐amyloid peptides and their aggregation in brain is a hallmark of Alzheimer's disease. On page 1560 C. B. Park and co‐workers describe a strong suppression effect of graphitic carbon nitride (g‐C 3 N 4 ) toward β‐amyloid aggregation under light‐illumination. Photoexcited g‐C 3 N 4 generates reactive oxygen species and blocks further β‐amyloid aggregation by impacting conformational structure of β‐amyloid, rendering it a promising material for Alzheimer therapy.

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