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Cellular Microcultures: Programming Mechanical and Physicochemical Properties of 3D Hydrogel Cellular Microcultures via Direct Ink Writing (Adv. Healthcare Mater. 9/2016)
Author(s) -
McCracken Joselle M.,
Badea Adina,
Kandel Mikhail E.,
Gladman A. Sydney,
Wetzel David J.,
Popescu Gabriel,
Lewis Jennifer A.,
Nuzzo Ralph G.
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201670043
Subject(s) - self healing hydrogels , inkwell , materials science , fibroblast , nanotechnology , biomedical engineering , composite material , chemistry , polymer chemistry , in vitro , medicine , biochemistry
R. Nuzzo and co‐workers show on page 1025 how compositional differences in hydrogels are used to tune their cellular compliance by controlling their polymer mesh properties and subsequent uptake of the protein poly‐ l ‐lysine (green spheres in circled inset). The cover image shows pyramid micro‐scaffolds prepared using direct ink writing (DIW) that differentially direct fibroblast and preosteoblast growth in 3D, depending on cell motility and surface treatment.