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Biomanufacturing Seamless Tubular and Hollow Collagen Scaffolds with Unique Design Features and Biomechanical Properties
Author(s) -
Singh Anirudha,
Lee David,
Sopko Nikolai,
Matsui Hotaka,
Sabnekar Praveena,
Liu Xiaopu,
Elisseeff Jennifer,
Schoenberg Mark P.,
Pienta Kenneth,
Bivalacqua Trinity J.
Publication year - 2017
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201601136
Subject(s) - biomanufacturing , process (computing) , computer science , tissue engineering , nanotechnology , biomedical engineering , materials science , engineering , biology , operating system , genetics
A versatile process to develop designer collagen scaffolds for hollow and tubular tissue engineering applications is presented. This process creates seamless and biomechanically tunable scaffolds ranging from ureter‐like microsized tubings to structures with highly customized lumens that resemble intestinal villi, fluid bladders, and alveolar sacs that together with stem cells can potentially be used in preclinical and clinical settings.