Chitosan‐Gated Magnetic‐Responsive Nanocarrier for Dual‐Modal Optical Imaging, Switchable Drug Release, and Synergistic Therapy | Zendy

Wang Hui | Zendy; Mu Qingxin | Zendy; Revia Richard | Zendy; Wang Kui | Zendy; Zhou Xuezhe | Zendy; Pauzauskie Peter J. | Zendy; Zhou Shuiqin | Zendy; Zhang Miqin | Zendy

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Chitosan‐Gated Magnetic‐Responsive Nanocarrier for Dual‐Modal Optical Imaging, Switchable Drug Release, and Synergistic Therapy

Author(s) -

Wang Hui,

Mu Qingxin,

Revia Richard,

Wang Kui,

Zhou Xuezhe,

Pauzauskie Peter J.,

Zhou Shuiqin,

Zhang Miqin

Publication year - 2017

Publication title -

advanced healthcare materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.288

H-Index - 90

eISSN - 2192-2659

pISSN - 2192-2640

DOI - 10.1002/adhm.201601080

Subject(s) - nanocarriers , chitosan , materials science , drug delivery , nanotechnology , drug , dual function , nanostructure , targeted drug delivery , drug carrier , biomedical engineering , chemistry , pharmacology , medicine , computer science , organic chemistry , computer graphics (images) , contouring

A dual‐layer shell hollow nanostructure as drug carrier that provides instant on/off function for drug release and contrast enhancement for multimodal imaging is reported. The on‐demand drug release is triggered by irradiation of an external magnetic field. The nanocarrier also demonstrates a high drug loading capacity and synergistic magnetic‐thermal and chemotherapy.

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