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Chitosan‐Gated Magnetic‐Responsive Nanocarrier for Dual‐Modal Optical Imaging, Switchable Drug Release, and Synergistic Therapy
Author(s) -
Wang Hui,
Mu Qingxin,
Revia Richard,
Wang Kui,
Zhou Xuezhe,
Pauzauskie Peter J.,
Zhou Shuiqin,
Zhang Miqin
Publication year - 2017
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201601080
Subject(s) - nanocarriers , chitosan , materials science , drug delivery , nanotechnology , drug , dual function , nanostructure , targeted drug delivery , drug carrier , biomedical engineering , chemistry , pharmacology , medicine , computer science , organic chemistry , computer graphics (images) , contouring
A dual‐layer shell hollow nanostructure as drug carrier that provides instant on/off function for drug release and contrast enhancement for multimodal imaging is reported. The on‐demand drug release is triggered by irradiation of an external magnetic field. The nanocarrier also demonstrates a high drug loading capacity and synergistic magnetic‐thermal and chemotherapy.