Premium
Single Cell Microgel Based Modular Bioinks for Uncoupled Cellular Micro‐ and Macroenvironments
Author(s) -
Kamperman Tom,
Henke Sieger,
van den Berg Albert,
Shin Su Ryon,
Tamayol Ali,
Khademhosseini Ali,
Karperien Marcel,
Leijten Jeroen
Publication year - 2017
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201600913
Subject(s) - modular design , biofabrication , computer science , modularity (biology) , nanotechnology , materials science , engineering , tissue engineering , programming language , biology , biomedical engineering , genetics
Modular bioinks based on single cell microgels within distinct injectable prepolymers enable uncoupling of biomaterials' micro‐ and macroenvironments. These inks allow biofabrication of 3D constructs that recapitulate the multiscale modular design of native tissues with a single cell resolution. This approach represents a major step forward in endowing engineered constructs with the multifunctionality that underlies the behavior of native tissues.