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Using a Redox Modality to Connect Synthetic Biology to Electronics: Hydrogel‐Based Chemo‐Electro Signal Transduction for Molecular Communication
Author(s) -
Liu Yi,
Tsao ChenYu,
Kim Eunkyoung,
Tschirhart Tanya,
Terrell Jessica L.,
Bentley William E.,
Payne Gregory F.
Publication year - 2017
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201600908
Subject(s) - redox , signal transduction , signal (programming language) , materials science , biophysics , nanotechnology , capacitor , substrate (aquarium) , microbiology and biotechnology , biology , computer science , physics , ecology , quantum mechanics , voltage , metallurgy , programming language
A hydrogel‐based dual film coating is electrofabricated for transducing bio‐relevant chemical information into electronical output. The outer film has a synthetic biology construct that recognizes an external molecular signal and transduces this input into the expression of an enzyme that converts redox‐inactive substrate into a redox‐active intermediate, which is detected through an amplification mechanism of the inner redox‐capacitor film.