Ebola Vaccination Using a DNA Vaccine Coated on PLGA‐PLL/γPGA Nanoparticles Administered Using a Microneedle Patch | Zendy

Yang HungWei | Zendy; Ye Ling | Zendy; Guo Xin Dong | Zendy; Yang Chinglai | Zendy; Compans Richard W. | Zendy; Prausnitz Mark R. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Ebola Vaccination Using a DNA Vaccine Coated on PLGA‐PLL/γPGA Nanoparticles Administered Using a Microneedle Patch

Author(s) -

Yang HungWei,

Ye Ling,

Guo Xin Dong,

Yang Chinglai,

Compans Richard W.,

Prausnitz Mark R.

Publication year - 2017

Publication title -

advanced healthcare materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.288

H-Index - 90

eISSN - 2192-2659

pISSN - 2192-2640

DOI - 10.1002/adhm.201600750

Subject(s) - immunogenicity , dna vaccination , plga , vaccination , nasal administration , nanoparticle , medicine , materials science , adjuvant , virology , immune system , pharmacology , immunization , nanotechnology , immunology

Ebola DNA vaccine is incorporated into PLGA‐PLL/γPGA nanoparticles and administered to skin using a microneedle (MN) patch. The nanoparticle delivery system increases vaccine thermostability and immunogenicity compared to free vaccine. Vaccination by MN patch produces stronger immune responses than intramuscular administration.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research