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A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus
Author(s) -
Jung Il Young,
You Jae Bem,
Choi Bo Ram,
Kim Ji Su,
Lee Hyun Kyung,
Jang Bora,
Jeong Han Saem,
Lee Kyuri,
Im Sung Gap,
Lee Hyukjin
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201600334
Subject(s) - loop mediated isothermal amplification , middle east respiratory syndrome , computer science , polymerization , covid-19 , nanotechnology , materials science , dna , chemistry , medicine , disease , pathology , infectious disease (medical specialty) , biochemistry , composite material , polymer
Trail polymerization enables a significant enhancement of the DhITACT system . DhITACT‐Trail (DNA hydrogel formation by isothermal amplification of complementary targets trail polymerization) offers a robust diagnosis of target RNA strands in pseudo‐serum specimen. This system requires minimum liquid handling as compared to conventional analysis. In addition, a definitive diagnostic result can be achieved within 30 min by an optical detection.