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Polydopamine Hollow Nanoparticle Functionalized with N ‐diazeniumdiolates as a Nitric Oxide Delivery Carrier for Antibacterial Therapy
Author(s) -
Park Dongsik,
Kim Jihoon,
Lee Yeong Mi,
Park Junghong,
Kim Won Jong
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201600150
Subject(s) - biocompatible material , nanotechnology , biocompatibility , nanoparticle , nitric oxide , drug delivery , materials science , combinatorial chemistry , chemistry , medicine , biomedical engineering , organic chemistry , metallurgy
A biocompatible nitric oxide (NO) delivery nanoplatform , whose structure is a hollow nanoparticle composed of polydopamine backbone and diazeniumdiolates functional groups, is developed for antibacterial therapy. This platform liberates high NO quantitis and exerts the antibacterial activity with excellent biocompatibility thus being promising for treating bacterial infections.