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Pharmaceutical Nanotechnology: Blended Nanoparticle System Based on Miscible Structurally Similar Polymers: A Safe, Simple, Targeted, and Surprisingly High Efficiency Vehicle for Cancer Therapy (Adv. Healthcare Mater. 8/2015)
Author(s) -
Tao Wei,
Zhang Jinxie,
Zeng Xiaowei,
Liu Danny,
Liu Gan,
Zhu Xi,
Liu Yanlan,
Yu Qingtong,
Huang Laiqiang,
Mei Lin
Publication year - 2015
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201570050
Subject(s) - materials science , nanoparticle , polyethylene glycol , ethylene glycol , polymer , plga , peg ratio , nanotechnology , biodegradable polymer , chemical engineering , composite material , finance , engineering , economics
On page 1203, a novel blended nanoparticle (NP) system for the delivery of anticancer drugs and its surprisingly high efficacy for cancer chemotherapy by blending a targeting polymer folic acid‐poly(ethylene glycol)‐b‐poly(lactide‐co‐glycolide) (FA‐PEG‐b‐PLGA) and a miscible structurally similar polymer D‐α‐tocopheryl polyethylene glycol 1000 succinate‐poly(lactide‐co‐glycolide) (TPGS‐PLGA) are reported by X. Zeng, L. Huang, L. Mei, and colleagues. This blended NP system can be achieved through a simple and effective nanoprecipitation technique, possessing unique properties.