Cancer Theranostics: Facile Preparation of Doxorubicin‐Loaded Upconversion@Polydopamine Nanoplatforms for Simultaneous In Vivo Multimodality Imaging and Chemophotothermal Synergistic Therapy (Adv. Healthcare Mater. 4/2015) | Zendy

Liu Fuyao | Zendy; He Xiuxia | Zendy; Lei Zhen | Zendy; Liu Liang | Zendy; Zhang Junping | Zendy; You Hongpeng | Zendy; Zhang Huimao | Zendy; Wang Zhenxin | Zendy

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Cancer Theranostics: Facile Preparation of Doxorubicin‐Loaded Upconversion@Polydopamine Nanoplatforms for Simultaneous In Vivo Multimodality Imaging and Chemophotothermal Synergistic Therapy (Adv. Healthcare Mater. 4/2015)

Author(s) -

Liu Fuyao,

He Xiuxia,

Lei Zhen,

Liu Liang,

Zhang Junping,

You Hongpeng,

Zhang Huimao,

Wang Zhenxin

Publication year - 2015

Publication title -

advanced healthcare materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.288

H-Index - 90

eISSN - 2192-2659

pISSN - 2192-2640

DOI - 10.1002/adhm.201570021

Subject(s) - photothermal therapy , materials science , in vivo , doxorubicin , nanotechnology , polyethylene glycol , nanoparticle , surface modification , peg ratio , drug delivery , biomedical engineering , medicine , chemotherapy , chemistry , surgery , microbiology and biotechnology , biology , organic chemistry , finance , economics

On page 559, H. M. Zhang, Z. X. Wang, and colleagues directly coat polydopamine (PDA) on hydrophobic upconversion nanoparticle (UCNP) to form UCNP@PDA core–shell nanosphere via a microemulsion approach, further modified with polyethylene glycol (PEG). After loading with DOX, the UCNP@PDA‐PEG‐DOX can completely eradicate mouse‐bearing colorectal cancer without regrowth guided by multimodal imaging, demonstrating highly effective combined photothermal and chemotherapy of the nanocomposites.

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