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Cell Migration: Tapered Microtract Array Platform for Antimigratory Drug Screening of Human Glioblastoma Multiforme (Adv. Healthcare Mater. 3/2015)
Author(s) -
Cha Junghwa,
Koh Ilkyoo,
Choi Yemuk,
Lee Jungwhoi,
Choi Chulhee,
Kim Pilnam
Publication year - 2015
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201570015
Subject(s) - glioblastoma , white matter , materials science , medicine , cancer research , magnetic resonance imaging , radiology
Histopathologically, brain tumor cells, especially glioblastoma multiform (GBM) cells, migrate along the orientation of thin, elongated anatomical structures, such as white‐matter tracts. On page 405, P. Kim and team show how the thinnest width of tapered microtract array platform can induce the in vivo saltatory migration of brain tumor cells, as in white matter tract.