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A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention
Author(s) -
Lee YoungAh Lucy,
Zhang Shiyi,
Lin Jiaqi,
Langer Robert,
Traverso Giovanni
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201501036
Subject(s) - janus , materials science , nanotechnology , biofouling , chemistry , membrane , biochemistry
A novel Janus device with omniphobic and mucoadhesive sides that exhibit the unique capacity for antifouling and extended gastrointestinal retention is fabricated . This system enables repulsion of the food and fluid stream by the luminal‐facing omniphobic side and allows attachment to the gastrointestinal mucosa by the mucoadhesive side.