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Viruses, Artificial Viruses and Virus‐Based Structures for Biomedical Applications
Author(s) -
van Rijn Patrick,
Schirhagl Romana
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201501000
Subject(s) - virology , virus , computational biology , biology
Nanobiomaterials such as virus particles and artificial virus particles offer tremendous opportunities to develop new biomedical applications such as drug‐ or gene‐delivery, imaging and sensing but also improve understanding of biological mechanisms. Recent advances within the field of virus‐based systems give insights in how to mimic viral structures and virus assembly processes as well as understanding biodistribution, cell/tissue targeting, controlled and triggered disassembly or release and circulation times. All these factors are of high importance for virus‐based functional systems. This review illustrates advances in mimicking and enhancing or controlling these aspects to a high degree toward delivery and imaging applications.