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Photoactive g‐C 3 N 4 Nanosheets for Light‐Induced Suppression of Alzheimer's β‐Amyloid Aggregation and Toxicity
Author(s) -
Chung You Jung,
Lee Byung Il,
Ko Jong Wan,
Park Chan Beum
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201500964
Subject(s) - graphitic carbon nitride , amyloid (mycology) , computer science , aggregation induced emission , chemistry , nanotechnology , materials science , photocatalysis , photochemistry , fluorescence , physics , biochemistry , catalysis , inorganic chemistry , quantum mechanics
Graphitic carbon nitride (g‐C 3 N 4 ) has a suppressive capability toward Alzheimer's Aβ aggregation under light‐illumination. Photoinduced electrons of g‐C 3 N 4 generate reactive oxygen resulting in photooxidation of amyloid peptides that blocks Aβ aggregation. Fe doping of g‐C 3 N 4 frameworks results in enhanced optical properties and even stronger inhibition of Aβ aggregation.