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pH‐Responsive Fe(III)–Gallic Acid Nanoparticles for In Vivo Photoacoustic‐Imaging‐Guided Photothermal Therapy
Author(s) -
Zeng Jianfeng,
Cheng Ming,
Wang Yong,
Wen Ling,
Chen Ling,
Li Zhen,
Wu Yongyou,
Gao Mingyuan,
Chai Zhifang
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201500898
Subject(s) - photothermal therapy , photoacoustic imaging in biomedicine , gallic acid , nanoparticle , in vivo , nanotechnology , absorbance , biocompatible material , materials science , computer science , chemistry , biomedical engineering , organic chemistry , medicine , optics , chromatography , biology , physics , microbiology and biotechnology , antioxidant
pH‐responsive biocompatible Fe(III)–gallic acid nanoparticles with strong near‐infrared absorbance are very stable in mild acidic conditions, but easily decomposed in neutral conditions, which enables the nanoparticles to be stable in a tumor and easily metabolized in other organs, thus providing a safe nanoplatform for in vivo photoacoustic imaging/photothermal therapy theranostic applications.