Polyanionic Macromolecular Prodrugs of Ribavirin: Antiviral Agents with a Broad Spectrum of Activity | Zendy

Hinton Tracey M. | Zendy; Zuwala Kaja | Zendy; Deffrasnes Celine | Zendy; Todd Shawn | Zendy; Shi Shuning | Zendy; Marsh Glenn A. | Zendy; Dearnley Megan | Zendy; Wohl Benjamin M. | Zendy; Tolstrup Martin | Zendy; Zelikin Alexander N. | Zendy

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Polyanionic Macromolecular Prodrugs of Ribavirin: Antiviral Agents with a Broad Spectrum of Activity

Author(s) -

Hinton Tracey M.,

Zuwala Kaja,

Deffrasnes Celine,

Todd Shawn,

Shi Shuning,

Marsh Glenn A.,

Dearnley Megan,

Wohl Benjamin M.,

Tolstrup Martin,

Zelikin Alexander N.

Publication year - 2016

Publication title -

advanced healthcare materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.288

H-Index - 90

eISSN - 2192-2659

pISSN - 2192-2640

DOI - 10.1002/adhm.201500841

Subject(s) - ribavirin , broad spectrum , prodrug , macromolecule , virology , materials science , nanotechnology , combinatorial chemistry , chemistry , virus , pharmacology , medicine , biochemistry , hepatitis c virus

Macromolecular prodrugs are developed as multiarmed agents against diverse viral pathogens. Lead candidates inhibit infectivity and replication of HIV, Ebola, influenza, measles, RSV, etc—thus being broad‐spectrum antiviral agents.

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