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Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood
Author(s) -
Shin DongSik,
Matharu Zimple,
You Jungmok,
Siltanen Christian,
Vu Tam,
Raghunathan Vijay Krishna,
Stybayeva Gulnaz,
Hill Ashley E.,
Revzin Alexander
Publication year - 2016
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201500571
Subject(s) - self healing hydrogels , nanotechnology , computer science , materials science , conductive polymer , polymer , electrical conductor , monoclonal antibody , polymer chemistry , antibody , medicine , immunology , composite material
Conducting polymer hydrogel is fabricated atop gold or ITO electrodes and is functionalized with monoclonal antibodies. Binding of interferon‐γ molecules causes redox properties of conductive hydrogel to change in a concentration‐dependent fashion without the need for washing or sample handling steps. This conductive hydrogel remains functional in a fouling media such as whole blood.