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Switchable Release of Entrapped Nanoparticles from Alginate Hydrogels
Author(s) -
Kearney Cathal J.,
Skaat Hadas,
Kennedy Stephen M.,
Hu Jennifer,
Darnell Max,
Raimondo Theresa M.,
Mooney David J.
Publication year - 2015
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201500254
Subject(s) - science and engineering , engineering , engineering ethics
Natural biological processes are intricately controlled by the timing and spatial distribution of various cues. To mimic this precise level of control, the physical sizes of gold nanoparticles are utilized to sterically entrap them in hydrogel materials, where they are subsequently released only in response to ultrasound. These nanoparticles can transport bioactive factors to cells and direct cell behavior on‐demand.